中国低出生体重儿危险因素的病例对照研究  

A case-control study on risk factors for low birth weight in China

作　　者：张新利[1] 刘玉琳[1] 林良明[1] 曹兰华[1] 米杰[1] 

机构地区：[1]首都儿科研究所流行病学研究室,北京100020

出　　处：《中华预防医学杂志》2002年第3期158-160,共3页Chinese Journal of Preventive Medicine

摘　　要：目的　探讨我国不同特征低出生体重儿发生的有关危险因素。方法　 1998年 7～ 10月 ,对我国 11个省 4 4个县市的 999例低出生体重儿进行 1∶1病例对照研究。结果　我国低体重儿发生的危险因素主要为多胎、孕周不足、孕期异常、孕期营养差、母亲疾病史及母亲文化程度低等 ,其OR值分别为 10 6 9、18 79、3 4 2、1 93、2 6 1和 1 4 3。各危险因素在沿海、内地及边远地区的分布差异有显著性。农村低体重儿的原因主要为宫内发育迟缓 (71 6 % ) ,城市低体重儿的原因还包括多胎和早产。早产及宫内发育不全的低出生体重儿之间的危险因素存在差异。结论　有针对性地开展防治工作是降低我国低体重儿出生率的有效措施。Objective To identify the risk factors for low birth weight (LBW) in Chinese newborns with varied characteristics Methods A 1∶1 matched case control study, with 999 babies of LBW was performed in 44 counties of 11 provinces in China during July to October, 1998 for identifying their risk factors using simple and multivariate logistic regression models Results The determinants of LBW in China included factors, such as multiparity ( OR =106 9), preterm birth ( OR =18 7), abnormal maternal health status ( OR =2 61) and maternal malnutrition ( OR =3 42), maternal medical conditions during pregnancy ( OR =1 93), maternal schooling ( OR =1 43), et al Distribution of the risk factors for LBW was significantly different between coastal, inland and remote areas LBW was mainly attributed to intrauterine growth retardation (IUGR) (71 6%) in the rural areas, and to multiparity and preterm birth, in addition to IUGR, in the urban areas There was different in the risk factors for LBW with preterm births and IUGR Conclusions It is an effective way to reduce incidence of low birth weight in China that all measures for prevention and control should be relevant to its risk factors

关 键 词：低出生体重 危险因素 病例对照研究 胎儿生长迟缓 新生儿 早产儿 

分 类 号：R714.7[医药卫生—妇产科学]