广西1～6岁儿童脑性瘫痪患病状况研究  

Prevalence of cerebral palsy in children aged 1-6 in Guangxi, China

作　　者：梁友玲[1] 郭先鸣[1] 杨广林[1] 颜秀梅 李小丽 李广邕[4] 兰东屏 李淑先 王勇[1] 丁浩平[1] 刘艳玲[1] 刘建蒙 李松 林庆[6] 

机构地区：[1]广西壮族自治区妇幼保健院,南宁530003 [2]广西壮族自治区横县妇幼保健院儿科 [3]广西壮族自治区钦州市钦北区妇幼保健院儿科 [4]广西壮族自治区南宁市妇幼保健院儿保科 [5]中国妇婴保健中心 [6]北京大学第一临床医院儿科

出　　处：《中华预防医学杂志》2002年第3期164-166,共3页Chinese Journal of Preventive Medicine

基　　金：国家"九五"医学科技攻关项目 (96 90 4 0 3 )

摘　　要：目的　调查广西 1～ 6岁儿童脑性瘫痪 (脑瘫 )的患病状况、流行特征以及相关危险因素。方法　采用随机整群抽样法 ,于 1998年 6～ 12月对广西南宁市、横县、钦州县 1～ 6岁儿童进行脑瘫患病状况及病因调查分析。结果　两县一市共调查 1～ 6岁儿童 15 0 80 6人 ,其中男 894 18人 ,女6 1388人。诊断为脑瘫者 193例 ,患病率为 1 2 8‰ ,其中男性 136例 ,患病率为 1 5 2‰ ,女性 5 7例 ,患病率为 0 93‰。男性显著高于女性。本组脑瘫的危险因素为 :出生不会哭 (出生窒息 )、Apgar评分小于 8分、分娩医疗机构级别、母亲怀孕次数、产前未作检查、孕期服退热药及食用腌制品数量等。结论　广西地区脑瘫患病率与国内外相比处于较低水平 ,这可能与该地区高危新生儿存活率较低、婴儿死亡率较高有关。Objective To study the prevalence of cerebral palsy (hereinafter referred to CP) in children aged 1-6 in Guangxi, China, and its epidemiologic characteristics and relevant risk factors Methods Investigations on the prevalence and etiology of CP in children at ages of 1-6 were conducted in Nanning, Hengxian and Qinzhou of Guangxi from June to December in 1998, with a cluster sampling Results Totally, 150 806 children aged 1-6 were investigated in Nanning, Hengxian and Qinzhou of Guangxi, with 89 418 boys and 61 388 girls Among them, 193 children were diagnosed as CP, with a prevalence rate of 1 28‰, higher in boys (136 cases, 1 52‰) than in girls (57 cases, 0 93‰), with statistical significance (χ 2=9 536 7, P =0 02) Logistic regression analysis showed that risk factors for CP were children who could not cry after birth (neonatal asphyxia), Apgar score less than eight, delivery at lower level of maternity hospital, number of mother′s gravidity, no prenantal checks for mothers, and taking antipyretics and preserved food with salt during pregnancy Conclusions Prevalence of CP in children of Guangxi was at a lower level in comparison with that in other areas at home and abroad, which, maybe, was related with the lower neonatal survival and higher infant mortality

关 键 词：脑性瘫痪 儿童 危险因素 抽样研究 

分 类 号：R179[医药卫生—妇幼卫生保健]