米索前列醇不同给药途径配合米非司酮终止早孕的效果观察  

Observing misoprostol and mifepristone different way's clinical effect

作　　者：丁少娜 

机构地区：[1]浙江省平阳县中医院妇产科,浙江平阳325400

出　　处：《河北医学》2002年第2期122-124,共3页Hebei Medicine

摘　　要：目的 :为了观察米索前列醇不同给药途径配伍米非司酮终止早孕的临床效果。方法 :选择停经 4 9d以内 ,年龄在 35岁以下 ,无米索服药禁忌症的早孕妇女 82例。随机分成A组和B组 :A组 4 0例口服米索前列醇及米非司酮予药物流产。B组 4 2例米索前列醇阴道与口服合并给药配伍米非司酮。结果 :两组的流产成功率分别为 90 %与 95 .2 %。两组比较。差异无显著性 (P >0 .0 5 ) ,但其流产时间分别为 5 .4 5±l.4 0h和 3.2 1±l.5 1h(P <0 .0 0 1) ,出血时间分别为 11.3± 2 .4d和 8.2± 2 .3d(P<0 .0 0 1)。结论 :采用米索前列醇口服合并阴道用药配合米非司酮要比单纯口服来得安全 。Objective: For observing misoprostol and mifepristone ciifferent way's dinical effect. Methods: Choosing the early pregnant women,sum up 82 cases,whose ages are under 35 years old.and amenorrhea are within 49 days. Separate there women in two groups casual. Term A and Term B. women,40 cases in Term A, who taking misoprostol to make abortion.women,42 cases in Term B,who taking mifepristone and putting misoprostol into vagina. Results: The rate of aboctive is 90% in Term A and 95.2% in Term B. Compare betneen A and B. Although there is no obvious difference, their abortive time is different: One is 5.45±1.40h and the other is 3.21±1.51h(P<0.001).The time of blood: 11.3d±2.4d and 8.2±2.3d(P<0.001). Conclusion: Adopting misoprostol and mifepristone will be safer and move effective than taking misoprostol medicine.

关 键 词：米索前列醇 米非司酮 早孕 给药途径 终止妊娠 药物引产 

分 类 号：R169.42[医药卫生—公共卫生与预防医学]