常压氧与高压氧联合疗法治疗重型颅脑损伤的作用  

Application of combination of normobaric and hyperbaric oxygen therapy in severe craniocerebral injury

作　　者：卢晓欣[1] 汤永建[1] 何苏育[1] 

机构地区：[1]解放军南京军区福州总医院,福建福州350025

出　　处：《中国临床康复》2002年第10期1410-1411,共2页Chinese Journal of Clinical Rehabilitation

摘　　要：目的探讨有并发症的重型颅脑损伤病人的合理氧疗方案,以提高治愈率和有效率。方法87例有高压氧治疗禁忌证的重型颅脑损伤病人分为两组,分别采用早期常压下面罩或呼吸活瓣吸纯氧(常压氧疗法)+高压氧的联合疗法和高压氧疗法两种方案治疗。结果常压氧+高压氧治疗组有效率、治愈率均高于高压氧组,其中治愈率差别具有显著意义(P<0.05);常压氧+高压氧组开始治疗的时间明显早于高压氧组,治疗开始的早晚与疗效直接相关,越早治疗治愈率越高。结论尽早合理应用常压氧+高压氧联合疗法,不失为促进伤后脑组织功能恢复、降低残死率和提高生存质量的有力措施之一。Objective To explore the oxygen therapy regime in severe craniocerebral injury patients so as to raise the healing rate a nd efficacy rate.Methods Eighty-seven sessions of craniocerebral injury patients with various a bstinences for hyperbaric oxygen th erapy were divided into two groups.One of the group(57sessions,group A)was treated with an early normobaric pure oxygen inhilation with face mask(normobaric oxygen therapy)followed by a hyperbaric oxygen therapy after the abstinences vanished a nd the other group(30sessions,group B)with merely a hyperbaric oxygen therapy.Efficacy rates as well as healin g rates were compared between the two groups.Results Both efficacy rate and healing rate were h igher in group A when compared with group B with the healing rate significant difference(P<0.05).Beginning of the treatment in group A was much earlier than in group B and th e earlier the oxygen therapy began,t he higher the healing rate.Conclusion A resonable application of normobaric and hyperbaric oxygen therapies a s early as possible was an effective measurement for accelerating the recovery of brain f unction,lowering the disablement r ate and mortality rate and raise the s urvival quality in servere cranio-cerebral injuries.

关 键 词：常压氧 高压氧 颅脑损伤 联合治疗 

分 类 号：R651.15[医药卫生—外科学] R459.6[医药卫生—临床医学]