小儿病毒性脑炎的病原研究  

A study on the etiology of children with viral encephalitis

作　　者：吉耀华[1] 何蓉[1] 李丽[1] 阮强[1] 刘庆[1] 魏洪斌[1] 

机构地区：[1]中国医科大学第二临床学院,辽宁沈阳110004

出　　处：《小儿急救医学》2002年第2期89-90,共2页Pediatric Emergency Medicine

摘　　要：目的　 探讨小儿病毒性脑炎的病原。 方法 　应用酶联免疫吸附方法 (ELISA)测定 5 1例病毒性脑炎患儿的脑脊液 (CSF)和血清中多种病毒特异性IgM抗体。 结果 　 5 1例病毒性脑炎患儿CSF中病毒IgM抗体阳性 2 1例 ( 4 1 2 %) ,血清中病毒IgM抗体阳性 18例 ( 35 3%)。 结论 　本地区病毒性脑炎多由肠道病毒和疱疹病毒引起 ,其中以CoxB和HSV为主要病原。Objective To study the etiology of viral encephalitis.Methods IgM antibodies were determined by enzyme-linked immunosorbent assay (ELISA) in the cerebral spinal fluid (CSF) and serum from 51 children with viral encephalitis.Results It was found that 21 CSF specimens were IgM positive (41\^2%), and 18 serum were IgM positive (35\^3%) to virus detected among 51 samples.Conclusion CoxB and HSV virus are the major causative agents of viral encephalitis in Shenyang.

关 键 词：病毒性脑炎 ELISA 脑脊液 小儿 病原 病毒IGM抗体 肠道病道 疱疹病毒 

分 类 号：R725.1[医药卫生—儿科]