不同温度及时间对液状保存血液质量的影响  

EFFECTS OF DIFFERENT TEMPERATURE AND TIME ON THE QUALITY OF BLOOD PRESERVATION IN LIQUID BLOOD

作　　者：杜静平[1] 裴兆辉[1] 马奎力[1] 邢凤有[1] 

机构地区：[1]佳木斯大学医学院病理生理教研室,黑龙江佳木斯154002

出　　处：《中国应用生理学杂志》2002年第2期186-189,共4页Chinese Journal of Applied Physiology

摘　　要：目的 :研究不同温度对血液液状保存时保存损害机制的影响 ,并探讨相应的防范措施。方法 :取 10名健康献血员静脉血 ,置于CP2D A保存液中 ,于 0℃和 4℃环境条件下 ,分别于设定的时间 (第 1周末、第 3周和第 6周末 )内取样检测GSH Px、LPO、TSH、红细胞膜收缩蛋白、膜脂流动性等指标。结果 :固定温度条件下随时间的延长血液过氧化反应增强 ,保存损害作用增加 ;同一时期内保存损害作用随温度的降低而减轻 ,以 4℃组血液老化明显。结论 :血液过氧化反应随保存期的延长而增加 ,随保存温度的降低而改善 ,0℃组保存血液的质量优于 4℃组。Aim: To explore the effects of different temperature and time on preservation damages in liquid blood. Methods: Take blood sample from 10 healthy blood donors, put the fresh blood into CP2D A liquid at 0℃ and 4℃, and take the samples after 1 week, 2 weeks and 3 weeks, and then measured the contents of GSH Px、TSH、LPO、the contracting protein of RBC, and membrane fluidity. Results: At the same temperatuve, when the preservation time is proloned, peroxidation is increased, the preservation damages are also augmented; the damages are declined when the temperature is lower during the same period, the aging of blood was more evident at 4℃.Conclusion: Blood peroxidation temperature is lower. The 0℃ group is better than 4℃ group.

关 键 词：温度 时间 液状保存 质量 血液保存 保存损害 

分 类 号：R457.1[医药卫生—治疗学]