北京市2000年人群麻疹抗体水平监测分析  

Surveillance of Measles Antibody Level of Population in Beijing 2000

作　　者：刘东磊[1] 王文胜[1] 董淑兰 王宝兰 黄德林 刘洪喜 刘秀军 万建波 卢莉[1] 辜荫华[1] 

机构地区：[1]北京市疾病预防控制中心,北京100013 [2]北京市海淀区卫生防疫站,北京100080 [3]北京市通州区卫生防疫站,北京101100 [4]怀柔县卫生防疫站,北京怀柔101400

出　　处：《中国计划免疫》2002年第1期27-29,共3页Chinese Journal of Vaccines and Immunization

摘　　要：开展人群免疫水平监测是麻疹监测工作的重要内容 ,对制定麻疹控制策略有重要意义。选择本市人口为监测对象 ,分为 10个年龄组 ,男女比例接近 1∶1,采用酶联免疫吸附试验 (ELISA)检测麻疹IgG抗体。共监测 30 9人 ,抗体阳性率为 84 5 % ,几何平均滴度 (GMT)为 1∶6 71 6。 <1岁婴儿麻疹抗体阳性率和GMT水平均最低 ,不同年龄组抗体阳性率和GMT水平有显著性差异。麻疹抗体阳性率和GMT水平有协同变化的趋势 ,而年龄对其无显著影响。麻疹低发病水平使人群接触麻疹病毒的机会减少 ,引起麻疹抗体反射性增高的可能随之降低 。To carry out the surveillance of immune level is an important content of measles surveillance,and it is also essential for working out an control strategy for measles We chose Beijing population as the subjects,and divided them into 10 age groups The sex ratio was nearly 1∶1. The measles virus specific IgG antibody was detected by the enzyme linked immunosorbent assay The total subjects were 309,and the positive rate of IgG antibody was 84 5%,the GMT was 1∶671 6 The seropositive rate and the GMT level were all the lowest in the cohort of 0 year old group and there was significant difference in different age groups The positive rate of IgG antibody had a trend in coordination with the GMT level,but the age factor had no influence to the both The low prevalence of measles made the possibility of virus contact and the antibody response decrease,and then followed by the decrement of infant's congenital maternal antibody

关 键 词：北京 抗体水平 麻疹 

分 类 号：R511.1[医药卫生—内科学]