应用背向散射积分技术检测急性心肌梗死的实验研究  

Animal study of the value of integrated backscatter on swine with acute myocardial infarction

作　　者：吴文霞[1] 陆凤翔[1] 朱莉[1] 许迪[1] 曹克将[1] 陈莉[1] 雍永宏[1] 周蕾[1] 

机构地区：[1]南京医科大学第一附属医院心内科,210029

出　　处：《江苏医药》2002年第6期426-428,共3页Jiangsu Medical Journal

摘　　要：目的　探讨超声组织定征 (UTC)背向散射积分 (IBS)技术对实验动物急性心肌梗死(AMI)的诊断价值。方法　HP550 0型超声诊断仪及S8探头 ,健康雄性小猪 1 2只 ,全麻下行冠脉左前降支 (LAD)闭塞 ,分别于术前、术后 1、2小时及 1周获取胸骨旁左室长轴、乳头肌短轴、心尖四腔和两腔的标准切面图像 ,测定IBS值、背向散射积分周期变化 (CVIB)、IBS周期变化跨壁梯度(TGCVIB)、周期变化延迟时间 (DTCV)及室壁增厚率 (△T % )的变化。结果　术后 1小时IBS %明显升高 ,DTCV %延长 ,CVIB %、TGCVIB和△T %明显降低 ;术后 2小时与 1小时无明显差别 ;术后 1周IBS %、DTCV %升高更明显 ,CVIB %、△T %减低更明显 ,而TGCVIB为负值。前壁IBS %、CVIB %分别与△T %行相关分析 ,相关系数分别为r =- 0 55 ,r =0 62 (P均 <0 0 1 ) ,DTCV %△T %也有一定的相关性 ,r =- 0 46(P <0 0 5)。结论　UTC背向散射技术可用于检测实验动物急性冠状动脉闭塞后心肌组织声学特征的改变 。Objective To assess the value of ultrasonic tissue characterization with integrated backscatter(IBS) on swine with acute myocardial infarction.Methods HP SONOS 5*!500 and probe S8 were used.Twelve swine were occluded in the left anterior descending (LAD),then the values of IBS,CVIB,TGCVIB,DTCV and △T% were performed pre occlusion,post 1 hour,2 hour and l week by acquiring the images of parathoratic long axis,short axis,apical 4 chamber and 2 chamber.Results The increase of IBS%,delay of DTCV and decrease of CVIB%,TGCVIB and △T% were observed post 1 hour.These changes were more significant post 1 week.Close relation could be observed between IBS% and △T%,between CVIB% and △T%,between DTCV% and △T%( r =-0 55, P <0 01; r =0 62, P <0 01; r =-0 46, P <0 05,respectiely).Conclusion IBS may detect the changes of myocardial acoustic characterization and can help to diagnose acute myocardial infarction.

关 键 词：背向散射积分 急性心肌梗死 诊断 治疗 实验研究 

分 类 号：R542.22[医药卫生—心血管疾病]