λ噬菌体阻遏蛋白与操纵基因相互作用的动力学研究  

The Kinetic Study on the Interactions of λ cI Repressor Protein with Operator

作　　者：丁辉[1] 李前忠[1] 

机构地区：[1]内蒙古大学理工学院物理系,内蒙古呼和浩特010021

出　　处：《内蒙古大学学报（自然科学版）》2002年第3期271-275,共5页Journal of Inner Mongolia University：Natural Science Edition

基　　金：内蒙古自然基金项目和国家自然基金项目

摘　　要：根据 λ噬菌体阻遏蛋白与操纵基因的相互作用特点 ,提出了他们相互作用的化学动力学模型 .用此模型计算各结合位点饱和分数与阻遏蛋白浓度的关系函数 ,并对λ噬菌体阻遏蛋白与操纵基因相互作用的本征自由能及各位点间的偶联自由能进行了估算 。According to the characteristics of the interactions of λ cI repressor proteins with operators,the chemical kinetic model of their interactions is proposed.The relations between the fractional saturation of every binding site and the concentrations of repressor proteins are given by using the model.And the intrinsic standard free energies of the interactions of λ cI repressor proteins with operators and the interaction energies of binding sites are calculated.These theoretical results are consistent with the experimental data.

关 键 词：Λ噬菌体 阻遏蛋白 操纵基因 结合位点 饱和分数 自由能 基因表达控制 相互作用运力学 

分 类 号：Q939.48[生物学—微生物学] Q756