伤速康涂膜剂提取工艺的实验研究  

Experimental study on Extraction Technology of SHANGSUKANG Membranes

作　　者：左亚杰[1] 倪春生[1] 邓满梅 陈维旗[1] 卢敏[1] 

机构地区：[1]湖南中医学院第一附属医院,湖南长沙410007 [2]长沙九芝堂制药厂,湖南长沙410007

出　　处：《湖南中医药导报》2002年第1期3-4,共2页Hunan Guiding Journal of Traditional Chinese Medicine and Pharmacology

基　　金：湖南省卫生厅中医药科研基金资助项目 (NO :9832 4 )

摘　　要：采用正交试验法 ,以大黄酸及醇提干浸膏得率为观察指标 ,对伤速康涂膜剂的提取工艺进行了实验研究。对大黄酸提取率、干浸膏得率影响最大的为乙醇浓度 ,其次是回流提取时间 ,乙醇量的影响不明显。经过综合评估 ,确定以 80 %乙醇提取 2次 ,第 1次加 4倍量乙醇回流提取 1.5h ,第 2次加 3倍量乙醇回流提取 1h为最佳提取工艺。Orthogonal experiment was used in study of the extraction technique of SHANGSUKANG membrane with the observation index of rhein and mellow dry extracting rates. As for the extracting rate of rhein and dry extracts, the ethanol thickness was the main effect, and the second one was the time of distilling circumfluence, while contents of ethanol had less influence on the effect. After comprehensive evaluation we have identified that the best extracting technique is the twice extractions with 80% ethanol. The first time the distill circumfluence duration is 1.5 hours with 4 times of ethanol. And the second time the distill circumfluence duration is 1 hour with 3 times of ethanol.

关 键 词：伤速康涂膜剂 提取工艺 大黄酸 干浸膏得率 正交试验 

分 类 号：R283.621[医药卫生—中药学]