新生儿高胆红素血症尿酶测定及临床意义  

A Clinical Significance for Detecting Urinary Enzyme in Neonatal Hyperbilirubinemia.

作　　者：马晓丹[1] 马坚[1] 舒蕾[1] 杨娅华[1] 徐文波[1] 山德生[1] 

机构地区：[1]云南省玉溪市人民医院新生儿科,云南玉溪653100

出　　处：《中国儿童保健杂志》2002年第2期109-110,共2页Chinese Journal of Child Health Care

摘　　要：【目的】　探讨新生儿高胆红素血症对肾小管功能的影响。　【方法】　对 3 5例高胆红素血症新生儿及 15例正常新生儿进行尿酶 (NAG、GAL)的测定。　【结果】　高胆红素血症新生儿尿酶含量明显高于对照组 ,且尿NAG含量与血清胆红素水平呈正相关。　【结论】　高胆红素血症可造成新生儿肾小管功能损害 ,尿酶的检测可以早期发现肾损伤 ,方法简便可靠 ,值得在临床上推广。To explore the influence of hyperbilirubinemia to the renal tubuler function in neonates. The levels of N acetyl β D glucosaminidase(NAG),β D galactosidase(GAL)in urine were detected in 35 cases of neonatal hyperbilirubinemia and 15 cases of normal newborn as control. Urinary NAG,GAL in neonates with hyperbilirubinemia group were much higher than that of the normal control group, and it showed a positive relation in the levels of NAG and the severity of hyperbilirubinemia. [Conclusion] The hyperbilirubinemia can result in renal tubular funtional lesion in the newborn. To determine urinary enzyme can find early stage of renal tubuler injury. This index are easy and reliable, can be wildly applicable in the clinic.

关 键 词：新生儿 高胆红素血症 肾损害 尿酶 

分 类 号：R722.17[医药卫生—儿科]