脐血中GM-CSF,IL-2,IL-6和sICAM-1的表达水平及意义  

THE LEVEL AND CLINICAL SIGNIFICANCE OF GM-CSF,IL-2,IL-6 AND sICAM-1 IN CORD BLOOD

作　　者：张新华[1] 朱凌[1] 蔡利群[1] 周天红[1] 甘柏柳[2] 杨萍[2] 徐杏美[2] 

机构地区：[1]解放军303医院,南宁530021 [2]南宁市妇幼保健院,南宁530023

出　　处：《中国现代医学杂志》2002年第8期55-56,共2页China Journal of Modern Medicine

基　　金：广西自然科学基金资助项目 (桂科自 9912 0 42 )

摘　　要：目的 :探讨GM -CSF、IL - 2、IL - 6和sICAM - 1在脐血中的含量及临床意义。方法 :采用ELISA法检测健康妇女血和脐血中GM -CSF、IL - 2、IL - 6和sICMA - 1的含量。结果 :脐血中GM -CSF、IL - 2和IL- 6的含量显著高于健康妇女血中含量 (P <0 .0 1) ,sICMA - 1则低于健康妇女 (P <0 .0 1)。结论 :脐血中有丰富的造血细胞因子 。Objective:To determine the level and clinical significance of GM-CSF,IL-2,IL-6 and sICAM-1 in cord blood. Methods:Enzyme linked immunosorbent assay was used to measure GM-CSF,IL-2,IL-6 and sICAM-1 in cord blood of healthy fetus and blood of healthy woman. Results:The level of GM-CSF,IL-2 and IL-6 in cord blood were all significantly higher than that in the blood of healthy woman (P<0.01),but sICAM-1 was significantly lower (P<0.01). Conclusions:There is abundant hematopoietic growth factor in the cord blood. It is safe and effective that the cord blood is used to treat leukopienia after chemotherapy or radiotherapy.

关 键 词：脐血 GM-CSF IL-2 IL-6 SICAM-1 

分 类 号：R551[医药卫生—血液循环系统疾病]