在胎儿发育过程中人MK基因的组织差异性表达  

Differential Expression of Human MK Gene During Embryogenesis

作　　者：林万敏[1] 唐以太[1] 陈献华[1] 郭兰萍[1] 徐平[1] 

机构地区：[1]复旦大学生命科学学院生理学及生物物理学系

出　　处：《复旦学报（自然科学版）》2002年第1期1-5,共5页Journal of Fudan University：Natural Science

摘　　要：MK是肝素结合因子家族中的一个成员 .用RT PCR研究了第 11～ 16周胎儿龄的胎儿的神经组织与非神经组织中MK基因的组织差异性表达 .随着胎儿龄的增加 ,在神经组织中 ,MK呈现出规律性的从无到有和从低表达到高表达的趋势 ,提示它可能在胎儿脑的发育中起着重要的作用 .在其他非神经组织中 ,尽管各组织中MK的表达呈现不同的规律 。MK is a member of heparin binding growth factor family. Using RT PCR, the differential expression of MK in neural and non neural tissues of the human embryos at various stages was studied. In neural tissues, the level of MK expression regularly increased following the embryonic development, suggesting that MK potentially play an important role in the development of fetal brain. Though the patterns of MK gene expression were different in non neural tissues, it seemed that the expression in these tissues tended to be activated in this period of time.

关 键 词：MK 发育过程 RT-PCR 胎儿 基因表达 神经组织 非神经组织 

分 类 号：Q132.7[生物学—普通生物学] R714.51[医药卫生—妇产科学]