电针促妊娠晚期大鼠子宫颈成熟的实验研究  

Experimental Study on Acupuncture for Promoting Cervical Ripening in the Third Trimester of Preg-nancy in Rats

作　　者：刘喆[1] 邓海平[1] 刘红菊[1] 

机构地区：[1]甘肃中医学院,兰州730000

出　　处：《中国针灸》2002年第6期409-411,共3页Chinese Acupuncture & Moxibustion

基　　金：本课题为甘肃省中青年科技基金资助项目(ZQ-96-14)

摘　　要：目的:探讨电针促宫颈成熟的效果与机理。方法:将妊娠晚期大鼠随机分为空白组、电针组、蓖麻油组和临产组。用高效液相色谱法测定宫颈羟脯氨酸含量,用放射免疫分析法测定羊膜前列腺素E2（PGE2）、血清白介素-6（IL-6）和白介素-8（IL-8）的含量。结果:电针显著降低了宫颈羟脯氨酸含量,显著升高了羊膜PGE2、血清IL-6和IL-8的含量。结论:电针具有促宫颈成熟的作用。其机理可能与升高羊膜PGE2、血清IL-6和IL-8的含量有关。Purpose To explore the effect and mechanism of acupuncture for promoting cervical ripening. Methods Rats in the third trimester of pregnancy were divided into 4 groups: control group, electroacupuncture group, castor oil diet group and parturient group. Hydroxyproline content of cervix uteri was measured by HPLC, prostaglanding E2 (PGE2) of amnion, and serum IL-6 and IL-8 contents were determined by radioimmunoassay. Results and Conclusion Electroacupuncture can improve cervical ripening, which is related possibly to contents of increase of PGE2 in amnion, serum IL-6 and IL-8 contents.

关 键 词：子宫颈 实验研究 针灸效应 妊娠末期 电针 

分 类 号：R246.3[医药卫生—针灸推拿学]