超长宽比岛状皮瓣血液灌注和氧代谢变化的实验研究  

A study of the pour blood and the oxygen metabolic in tissue for extra-artery fascia flap

作　　者：王佳琦[1] 管正玉[1] 刘珍君[1] 赵萍[1] 赵敏[1] 戚可名[1] 

机构地区：[1]中国医学科学院中国协和医科大学整形外科医院

出　　处：《中华整形外科杂志》2002年第3期155-156,I001,共3页Chinese Journal of Plastic Surgery

摘　　要：目的　探讨超长宽比岛状皮瓣的成活机理和血液灌注及氧代谢变化 ,以期掌握其成活规律。方法　以大白兔为实验动物模型 ,形成超长、宽比例的岛状皮瓣 ,分段测定血流和丙二醛(MDA)含量变化 ,以反映组织氧代谢过程。结果　血流量下降 ,MDA含量同步上升并呈渐进性 ,但皮瓣仍能较好的成活。只是达到一定程度才出现皮瓣坏死。结论　皮瓣从近端到远端血流量逐步减少和组织缺氧 ,并呈现渐进的过程 ,组织缺血和缺氧达到一定程度才会影响皮瓣的成活。所以掌握影响皮瓣成活的组织缺血和缺氧程度阈值 。Objective\ The aim of the work was to study the change for blood pour into the artery fascial flap and oxygen metabolic in tissue that knew the process of the flap. Methods\ We do the artery fascial flap in the rabbit,then measured the skin capillary blood flow and the content of the MDA. Results\ The content of the MDA rise when the blood flow descends in the flap,but it lives well. Conclusions\ That the content of the MDA rise as time the blood flow descend in the flap is a gradual process of the whole flap from tip to end,the flap will not appear necrosis until the MDA reach a rather degree.\;

关 键 词：超长宽比岛状皮瓣 血液灌注 氧代谢 实验研究 血流量 

分 类 号：R622[医药卫生—整形外科]