AES杀精作用及其对精子超微结构的影响  

SPERMATOCIDAL EFFECTS OF AES ON HUMAN SPERM IN VITRO AND THE ULTRASTRUCTURAL CHANGES OF THE AFFLICTED SPERM

作　　者：苗乃周[1] 郭仁舆[2] 

机构地区：[1]延安医学院组织胚胎学教研室 [2]西安医科大学组织胚胎学教研室

出　　处：《西安医科大学学报》1991年第2期113-115,共3页Journal of Xi'an Medical University(Chinese)

摘　　要：以脂肪醇聚氧乙烯醚硫酸钠(Fatty Alcohol Polyoxyethylene Ether So-dium Sulfate,AES)作为杀精子剂进行体外实验研究,结果表明,AES具有较强的杀精子效应,它使精子瞬间失活的最低有效浓度为0.08%。透射电镜观察证明,AES损害精子的主要靶结构是细胞膜、顶体和线粒体。Fatty Alcohal Polyoxyethylene Ether So-dium Sulfate (AES) was used as aspermatocide to elucidate its spermatocidal ef-fects on human sperm in vitro and theultrastructural changes of the afficted sperm.The results indicate that AES possessesstrong spermatocidal effects and can kill allthe spermatozoa within 1 min at a minimumeffective concentration of 0.08%. TEMobservation shows that the main targetstructures are plasma membrane, acrosomeand mitochondria.

关 键 词：AES 精子 杀精子剂 超微结构 

分 类 号：R321.1[医药卫生—人体解剖和组织胚胎学]