油乳法制备高效液相色谱氧化钛和钛锆氧化物复合填料  

Preparation of Titanium Dioxide and Titania-Zirconia Microsphere for HPLC Packing by Oil Emulsion Technology

作　　者：薛振东[1] 贺 飞[1] 冯钰锜[1] 

机构地区：[1]武汉大学化学与分子科学学院,湖北武汉430072

出　　处：《武汉大学学报（理学版）》2002年第2期142-146,共5页Journal of Wuhan University:Natural Science Edition

基　　金：国家自然科学基金资助项目(29875020)

摘　　要：以四氯化钛（TiCl4）和氧氯化锆（ZrOCl2·8H2O）为原料,采用油乳法制备了氧化钛和钛锆氧化物复合色谱填料.制备方法简单,条件易于控制,重现性好.用扫描电镜、X-粉末衍射、氮吸附法等方法研究了这两种氧化物微球的物理化学性质,表明所制得的多孔微球粒径分布窄（4-6μm）,孔径在中孔范围内（TiO5.8nm,TiO2-ZrO2　7.4nm）,机械性能良好（可承受41Mpa压力）,完全满足高效液相色谱的需要.Two kinds of titania-containing microspheres (pure titanium dioxide and titania-zirconia) were prepared by oil emulsion technology. Several factors influencing microsphere formation were studied. Electron microscopy, X-ray diffraction, nitrogen adsorption and potentiometric acid-base titration were used to evaluate the properties of the microparticles. The results indicated that the inorganic particles obtained can be used as packing material for HPLC because of their desired pore size(TiO2 5. 8 nm, TiO2-ZrO2 7. 4 nm), particle shape and relatively narrow particle size distribution(4-6 μm)with high mechanical and chemical stability.

关 键 词：钛锆氧化物复合填料 氧化钛 氧化锆 油乳法 高效液相色谱固定相 氧化物微球 孔径 机械性能 

分 类 号：O657.72[理学—分析化学]