^(99)Tc^m-MIBI透视三维显示诊断胸部病变的临床价值  

Clinical value of ^(99)Tc^m-MIBI SPECT and 3D display for evaluating malignant lesions in thorax

作　　者：文志道[1] 欧阳巧洪[1] 刘加昌[1] 张瑾[1] 范的 郭建中[2] 

机构地区：[1]解放军第304医院核医学科,北京100037 [2]解放军第304医院胸外科,北京100037

出　　处：《中华核医学杂志》2002年第2期114-115,I003,共3页Chinese Journal of Nuclear Medicine

摘　　要：目的　评估99Tcm 甲氧基异丁基异腈透视三维显示法对胸部恶性病变及其在相邻部位转移灶检出方面较平面及断层显像所具有的优势。方法　回顾性分析 5 4例恶性和 6例良性经手术或病理检查证实的胸部病变 ,并将SPECT透视三维法与X线胸片、CT等对照研究。结果　正常对照组 16例均为阴性 ;恶性病变组中肺癌 38例 ,平面显像阳性率 5 2 .6 % ,断层阳性率 78.9% ,透视三维法阳性率 84.2 % ;食管癌 12例 ,平面阳性率 41.6 % ,断层阳性率 5 8.3% ,透视三维法阳性率 75 .0 % ;4例纵隔及腋下恶性病变平面显像和X线无异常 ,CT阴性 ,透视三维法阳性。结论　透视三维法检出病灶优于平面和断层显像 ,与X线胸片、CT、纤支镜比较 ,灵敏度、特异性相对均衡 。Objective This study investigated the diagnostic accuracy of 99Tc m-MIBI and 3 dimension (3D) display (MIP) for evaluating the malignant lesions in thorax. Methods SPECT with 99Tc m-MIBI and 3D display were used to evaluate 16 normal subjects and 60 patients suspected with malignant lesions in the thorax. All patients also underwent X-ray and CT examinations. Results All images of 16 normal subjects were negative. In lung cancer group (38 cases), positive rate of planar scintigraphy, SPECT and 3D display were 52.6%, 78.9% and 84.2%, respectively. In esophagus cancer group (12 cases), positive rate were 41.6%, 58.3% and 75.0%. In other groups of lesions in mediastinum and in axillary fossae (4 cases), there was 100% positive by 3D display, but negative by planar scintigraphy, X-ray and CT. Conclusions SPECT imaging with 99Tc m-MIBI and 3D display is reliable. The sensitivity, specificity and accuracy of the method are superior to planar imaging, tomographic scintigraphy, X-ray and CT in distinguishing lesions in the thorax.

关 键 词：胸部肿瘤 MIBI 甲氧基异丁基异腈 诊断 ^99Tc^m-MIBI透视三维显示法 

分 类 号：R817[医药卫生—影像医学与核医学]