骨朗格罕斯细胞组织细胞增生症的细针吸取细胞学诊断  

Diagnosis of Langerhans'cell histiocytosis by fine needle aspiration cytology

作　　者：胡大学[1] 肖广成[1] 

机构地区：[1]四川省人民医院病理科,成都610071

出　　处：《医学科技》2002年第1期43-46,共4页

摘　　要：目的:探讨细针吸取细胞学(FNAC)在术前诊断骨 Langerhans 细胞组织细胞增生症(LCH)中的作用及意义。方法:用细针吸取采集肿瘤细胞涂片。经 HE、Wright 和免疫细胞化学染色、光镜观察,将术前 FNAC 结论与术后组织切片诊断进行对比分析。结果:细胞学诊断 LCH21例,其中19例进行了手术切除及病理切片检查,细胞学诊断准确率为94.7%。结论:骨 LCH 在FNAC 检查中具有特征性细胞形态学改变,术前诊断准确率高,且方法简便、快速,为临床手术治疗提供了有价值的细胞病理学依据。Objective:To study the role of preoperative fine needle aspiration cytology(FNAC)in the diagnosis of Langerhans'celI histiocytosis(LCH)of the bone.Methods:FNAC smears were stained with H&E,Wright staining and immunohistochemistry and observed under light microscope.Results: Twenty-one cases of LCH were diagnosed by FNAC,in which 19 cases were confirmed by postoperative histological examination.The sensitive rate of FNAC in diagnosis of LCH was 94.7%.Conclusion: FNAC is a rapid and useful technique for immdiated diagnosis of LCH that allows concurrent therapy.

关 键 词：Lagerhans细胞组织细胞增生症 骨 细针吸取细胞学 病理学 

分 类 号：R446.8[医药卫生—诊断学] R681[医药卫生—临床医学]