江西汉族人群D6S1043等9个STR基因座的遗传多态性研究  

A study of polymorphism of the9STR loci in Chinese Han population in Jiangxi

作　　者：赵会安[1] 刘小莹[1] 杨泉根[1] 

机构地区：[1]江西省公安厅刑事科学技术研究所,南昌330006

出　　处：《刑事技术》2002年第3期9-11,共3页Forensic Science and Technology

摘　　要：目的研究D6S1043、D8S1132、D11S2368、D7S3048、D18S1364、D20S478、D22-GATA198B05、D2S1772、D13S325共9个STR基因座遗传多态性。方法应用PCR扩增,聚丙稀酰胺垂直电泳及银染技术,对200例中国江西汉族人群上述9个STR基因座首次进行了检验分析。结果获得了中国江西汉族人群基因频率分布资料,基因频率分布符合Hardy-Weinberg平衡,杂合度(H)0.7830～0.8768,个体识别率(DP)0.9166～0.9680,非父排除率(PE)0.5795～0.7468,多态信息总量(PIC)0.7493～0.8616。结论D6S1043等9个STR基因座是一组高多态性的遗传标记系统,在法医学及人类遗传学研究中具有重要意义。Population genetic data of the9STR D6S1043?D8S1132?D11S2368?D7S3048?D18S1364?D20S478?D22-GATA198B05?D2S1772and D13S325loci in a sample of200unrelated individuals of Han population in Jiangxi was studied with the method of PCR and PAGE vertical electrophorsis and then silver staining.There is no significant deviation from the Hardy-Weinbery equilibrium.The H was0.7830～0.8768,DP0.9166～0.9680,PE0.5795～0.7468,PIC0.7493～0.8616.The results show that the9loci are very useful in the forensic sicence practice and genetic study.

关 键 词：江西汉族人群 D6S1043 STR基因座 遗传多态性 银染显带 

分 类 号：D919.1[医药卫生—法医学]