模拟醛缩酶催化不对称直接Aldol反应新进展  

Recent Progress in Aldolase-Mimic Catalyzed Direct Asymmetric Aldol Reaction

作　　者：张骥[1] 李蕾蕾[1] 罗美明[1] 谢如刚[1] 

机构地区：[1]四川大学化学系,成都610064

出　　处：《有机化学》2002年第5期318-326,共9页Chinese Journal of Organic Chemistry

摘　　要：对天然醛缩酶的作用机理进行了一般性阐述 ,在此基础上详细回顾了近几年对两类醛缩酶的模拟催化不对称直接Aldol反应 。Some recent progresses in the aldolase-mimic catalyzed direct asymmetric Aldol reaction are reviewed in detail, along with a general description of natural aldolase, including both type I and II. Several typical catalytic system such as L-proline, LLB and Zn(II)-semi-crown complexes were described and the catalytic abilities were compared. The prospects of this hot field are also discussed.

关 键 词：醛缩酶 醛醇缩合反应 不对称催化 直接ALDOL反应 模拟酶 

分 类 号：O643.3[理学—物理化学]