由D-Erythorbic Acid合成新的多官能团C_4手性筑块  

Synthesis of New Multifunctional Chiral C_4 Building Blocks from D-Erythorbic Acid

作　　者：李明霞[1] 王言明 陈茹玉[1] 

机构地区：[1]南开大学元素有机化学研究所,天津300071 [2]Pittsburgh University Medical Center

出　　处：《高等学校化学学报》2002年第6期1094-1096,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 9972 0 2 1)资助

摘　　要：Compounds 4 and 5 which were new selectively protected and multifunctional chiral C 4 building blocks were prepared conveniently from commercially available D erythorbic acid in no more than three steps with satisfied yields. Since compound 4 and compound 5 are densely functionalized and rich in stereochemistry, they are useful chiral building blocks in asymmetric synthesis.Compounds 4 and 5 which were new selectively protected and multifunctional chiral C 4 building blocks were prepared conveniently from commercially available D erythorbic acid in no more than three steps with satisfied yields. Since compound 4 and compound 5 are densely functionalized and rich in stereochemistry, they are useful chiral building blocks in asymmetric synthesis.

关 键 词：合成 多官能团C4手性筑块 D-erythorbicacid 有机合成 

分 类 号：O621.3[理学—有机化学]