异噁唑衍生物的新合成方法  

A Novel Synthesis of Isoxazoles Derivatives

作　　者：王俊锋[1] 彭云贵[1] 杜宝山[1] 

机构地区：[1]北京师范大学化学系,北京100875

出　　处：《高等学校化学学报》2002年第6期1097-1099,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :2 9672 0 0 4)资助

摘　　要：The 4 aryl 3,5 bis(methoxycarbonyl) 2 isoxazoline N oxides(nitrones)(a) in anhydrous DMF was refluxed for 3-4 hours and ten of 4 aryl 3,5 bis(methoxycarbonyl) 2 isoxazoles(b) were given with good yields(43%-81%) via thermolysis. All of the 4 arylisoxazoles were identified with IR, \{ 1H NMR\}, \{ 13 C NMR\}, MS and elemental analysis. A novel and convenient synthetic method of 4 arylisoxazol was porvided.The 4 aryl 3,5 bis(methoxycarbonyl) 2 isoxazoline N oxides(nitrones)(a) in anhydrous DMF was refluxed for 3-4 hours and ten of 4 aryl 3,5 bis(methoxycarbonyl) 2 isoxazoles(b) were given with good yields(43%-81%) via thermolysis. All of the 4 arylisoxazoles were identified with IR, \{ 1H NMR\}, \{ 13 C NMR\}, MS and elemental analysis. A novel and convenient synthetic method of 4 arylisoxazol was porvided.

关 键 词：异恶唑衍生物 合成方法 硝酮 热解反应 4-取代苯基异恶唑 

分 类 号：O626.24[理学—有机化学]