利用侧链修饰寡聚DNA组装CdS有序纳米结构  

Ordered Nanostructure of CdS Nanoparticles Assembled by 2′-Phosphorothioate Oligo-DNA

作　　者：杨百全[1] 江林[1] 杨文胜[1] 李铁津 李丕春 

机构地区：[1]吉林大学化学学院,长春130023 [2]吉林碳素工业集团教育培训中心,吉林132002

出　　处：《高等学校化学学报》2002年第6期1168-1170,共3页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金 (批准号 :60 1710 2 2 )资助

摘　　要：CdS nanoparticles were synthesized by using two complementary 2′ phosphorothioate oligo DNA, oligoG 10 SH and oligoC 10 SH as stabalizers. Because the thiol group was modified at phosphate site between C1 and C2 of 5′ end, the spatial exposure of DNA residue at C1 site was preponderant compating with the spatial exposure of the nanoparticles when the DNA renatured. The experimental result showed DNA renaturation ratio is about 50% and CdS nanoparticles were assembled into parallel quadrilateral array as the DNA renaturation progressed.CdS nanoparticles were synthesized by using two complementary 2′ phosphorothioate oligo DNA, oligoG 10 SH and oligoC 10 SH as stabalizers. Because the thiol group was modified at phosphate site between C1 and C2 of 5′ end, the spatial exposure of DNA residue at C1 site was preponderant compating with the spatial exposure of the nanoparticles when the DNA renatured. The experimental result showed DNA renaturation ratio is about 50% and CdS nanoparticles were assembled into parallel quadrilateral array as the DNA renaturation progressed.

关 键 词：组装 有序纳米结构 DNA CDS 纳米粒子 硫化镉 DNA芯片 

分 类 号：Q523[生物学—生物化学]