卤代-2-(3-甲基-5-取代-4H-1,2,4-三唑-4-基)-苯甲酸的合成  

Synthesis of Halogen Substituted-2-(3-methyl-5- substitued-4H-1,2,4-triazol-4-yl)benzoic Acid

作　　者：罗铁军[1] 李正名[2] 王素华[2] 廖仁安[2] 李之春[2] 

机构地区：[1]湖南化工研究院 [2]南开大学元素有机化学国家重点实验室,天津300071

出　　处：《应用化学》2002年第6期594-596,共3页Chinese Journal of Applied Chemistry

基　　金：国家自然科学重点基金 (2 983 2 0 5 0 );高等学校国家重点实验室访问学者基金资助课题

摘　　要：The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halogen substituted 2 (3 methyl 5 substitued 4H 1,2,4 triazol 4 yl) benzoic acid. All compounds synthesized were identified by 1H NMR and elemental analyses.The halogen substituted anthranilic acid(1) was condensed with acetic anhydride to give halogen substituted 3 methyl 1H 2,4 benoxazin 1 one(2), which was further condensed with hydrazide (3) to give twelve novel halogen substituted 2 (3 methyl 5 substitued 4H 1,2,4 triazol 4 yl) benzoic acid. All compounds synthesized were identified by 1H NMR and elemental analyses.

关 键 词：合成 卤代-2-(3-甲基-5-取代-4H-1 2 4-三唑-4-基)-苯甲酸 邻氨基苯甲酸 三唑 缩合反应 

分 类 号：O626.26[理学—有机化学]