饮食控制对中老年糖耐量减低者红细胞〔Ca^(2+)〕i水平的影响  

Effect of Diet on Erythrocyte〔Ca^(2+) 〕i in Elderly Subjects with Impaired Glucose Tolerance

作　　者：吴凤兰[1] 刘国宁[2] 张明珠[1] 黄俭[3] 张亚非[1] 吴赤蓬[2] 范存欣[2] 

机构地区：[1]暨南大学医学院营养教研室,广州510632 [2]暨南大学医学院卫生学教研室 [3]暨南大学第一附属医院营养科

出　　处：《中国公共卫生》2002年第6期691-692,共2页Chinese Journal of Public Health

摘　　要：目的　探讨饮食控制对中老年糖耐量减低者红细胞内游离钙浓度 (〔Ca2 + 〕i)的影响。方法　对 42例中老年糖耐量减低者进行为期 1 0个月的饮食干预。并在干预前后测定空腹血糖 (FSG)、2小时餐后血糖 (2HSG)、红细胞〔Ca2 + 〕i、血清甘油三酯 (TG)、总胆固醇 (TC)、糖化低密度脂蛋白 (G -LDL)和体质指数 (BMI)。结果　与糖耐量正常者比较 ,IGT患者红细胞〔Ca2 + 〕i显著升高 (P <0 0 1 )。饮食干预后 ,红细胞〔Ca2 + 〕i显著下降 (P <0 0 1 )。FSG、2HSG、TG、TC、G -LDL及BMI在干预后均显著下降。结论　饮食控制对IGT患者红细胞〔Ca2 + 〕i异常升高有明显的抑制作用。Objective To explore the effect of diet intervention on erythrocyte intracellular free calcium concentration(〔Ca 2+ 〕)i in subjects with impaired glucose tolerance(IGT).Methods Diet intervention trial was carried out in 42 subjects with IGT.The experiment period was 10 months.The erythrocyte 〔Ca 2+ 〕i,fasting serum glucose(FSG),2 hour serum glucose after 75g OGTT(2H SG),triglyceride(TG),cholesterol(TC),glycosylated low density lipoprotein(G LDL) of serum as well as body mass index(BMI) were observed on 2 occasions,before and 10 months after initiation of a diet intervention trial.Results The erythrocyte〔Ca 2+ 〕i in subjects with IGT was increased significantly compared with that of normal.The erythrocyte〔Ca 2+ 〕i,FSG?2HSG?TG?TC?G LDL levels as well as BMI decreased significantly in 42 subjects with IGT following diet intervention ( P <0 01).Conclusion The results suggest that diet intervention inhibits significantly the increase of erythrocyte〔Ca 2+ 〕i and the above change might be associated with the decrease of serum glucose caused by the diet intervention.

关 键 词：饮食干预 糖耐量减低 红细胞内游离钙 血糖代谢 糖尿病 

分 类 号：R587.1[医药卫生—内分泌]