枳椇子水提取液对四氯化碳致小鼠肝损伤的?ぷ饔?  

Protective Effects of the wter Extract form Hovenia dulcis Thunb. on CCl_4-induced Experimental Hepatic Injury

作　　者：嵇扬[1] 陆红[2] 

机构地区：[1]中国人民解放军总后勤部卫生部药品仪器检验所，北京100071 [2]中国人民解放军空军沈阳医院，辽宁沈阳110005

出　　处：《时珍国医国药》2002年第6期327-328,共2页Lishizhen Medicine and Materia Medica Research

摘　　要：目的 :了解枳木具子水提取液对四氯化碳致小鼠肝损伤的保护作用。方法 :在小鼠灌胃给予药液后 7d,腹腔注射四氯化碳 ,16 h后眼眶采血测定谷丙转氨酶 (ALT)、谷草转氨酶 (AST)、乳酸脱氢酶 (L DH)、胆固醇 (CH)、甘油三酯 (TG)等生化指标。通过比较药物组是否明显降低四氯化碳所致的生化指标异常升高 ,评价药物的保护作用。结果 :枳木具子水提取液明显降低四氯化碳所致的谷丙转氨酶、谷草转氨酶、乳酸脱氢酶等生化指标的异常升高。结论Objective:To investigate the protective effects of the water extract from Hovenia dulcis Thunb. (HDT) on carbon tetracholride (CCl 4) induced experimental hepatic injury in mice. Methods:The model of hepatic injury was induced by CCl 4. The biochemical indexes of serum ALT, AST, LDH, CH, TG were determined. Results:HDT significantly inhibited the rising of serum ALT, AST, LDH induced by CCl 4. Conclusion:HDT had significant protective effects on CCl 4 induced experimental hepatic injury.

关 键 词：枳JU子 四氯化碳 保肝作用 中药 

分 类 号：R285.5[医药卫生—中药学]