小麦非致病菌脂多糖对小鼠免疫功能的影响  

EFFECT OF PANTOEA AGGLOMERANS LIPOPLYSACCHARIDE ON IMMUNOLOGI-CAL FUNCTION

作　　者：黄志明[1] 黄仁彬[1] 陈家欢[1] 陈美芳[1] 杨斌[1] 黎肇炎[1] 王乃平[1] 

机构地区：[1]广西医科大学药理学教研室,南宁530021

出　　处：《广西医科大学学报》2002年第2期195-197,共3页Journal of Guangxi Medical University

基　　金：广西科学研究和技术开发项目 (桂科攻 98170 75 )

摘　　要：目的 :研究小麦非致病菌脂多糖 (Pantoea agglom erans lipoplysaccharide,L PSp)对小鼠免疫功能的影响。方法 :观察L PSp对小鼠免疫器官的重量、溶血素生成、碳粒廓清速率和 2 ,4 -二硝基氯苯迟发型超敏反应的影响。结果 :L PSp可增加小鼠免疫器官脾和胸腺重量 ,促进溶血素生成 ,提高小鼠网状内皮系统吞噬功能 ,以及显著抑制 2 ,4 -二硝基氯苯诱发的迟发型超敏反应 (P <0 .0 5或 P <0 .0 1)。结论 :LObjective: To study the effects of pantoea agglomerans lipoplysaccharide (LPSp) on immunological function of mice Methods: The weight of immune organs, the production of hemolysin, the clearance of charcoal particl, and the delayed hypersensitivity induced by 2,4 chlorodinitrobenzene were investigated after the treatment with LPSp Results: The results showed that YLS could significantly increase the weights of spleen and thymus gland, the level of hemolysin, and the index of phagocytosis of reticular endothelial system, and inhibit the delayed hypersensitivity induced by 2,4 chlorodinitrobenzene Conclusion: LPSp has an obvious effect of immunity enhancement

关 键 词：小麦非致病菌脂多糖 LPSP 溶血素 免疫功能 碳粒廓清速率 

分 类 号：R965[医药卫生—药理学]