老年人气管插管和气管切开患者绿脓杆菌对多种抗生素耐药比较  

Comparative of drug-resistant of pseudomonas aeruginosa in the elder patients with tracheal cannula and incision

作　　者：刘长庭[1] 秦荧[1] 王德龙[1] 

机构地区：[1]解放军总医院南楼呼吸科,北京100853

出　　处：《军医进修学院学报》2002年第2期104-106,共3页Academic Journal of Pla Postgraduate Medical School

摘　　要：目的 :比较老年人气管插管和切开患者绿脓杆菌对多种抗生素耐药。方法 :45例气管插管期间痰培养的 99株绿脓杆菌对多种抗生素耐药与 40例气管切开期间痰培养的 2 6 4株绿脓杆菌对多种抗生素耐药进行比较。结果 :气管切开患者绿脓杆菌对抗生素耐药比气管插管患者绿脓杆菌对抗生素耐药有所增加 ,其中丁胺卡那霉素、环丙沙星、磺苯咪唑青霉素、羧噻吩青霉素、妥布霉素耐药增加有显著统计学意义 (P <0 0 5 ,P <0 0 1) ;其他抗生素如氨曲南、羧苄青霉素、替门汀、头孢哌酮钠耐药也有所增加 ,未达到统计学意义。绿脓杆菌对头孢他啶及亚胺培南耐药变化不大。结论 :老年人气管切开患者绿脓杆菌对丁胺卡那霉素、环丙沙星、磺苯咪唑青霉素、羧噻吩青霉素、妥布霉素耐药率比气管插管患者的耐药率增加 ,对头孢他啶及亚胺培南耐药变化不大。Objective:Compared of drug-resistant of pseudomonas aeruginosa in the elder patients with tracheal cannula and incision. Methods: 99 strains drug sensitivity tests of pseudomonas aeruginosa in the elder patients with 45 cases tracheal cannula compared with 264 strains drug sensitivity in the elder patients with 40 cases tracheal incision. Results:Drug-resistant of pseudomonas aeruginosa in the elder patients with tracheal incision compared with tracheal cannula was increase. The drug-resistant rates of amikacin, ciprofloxacin, meziocillin, ticarcillin, tobramycin were increase significantly in the patients with tracheal incision compared with tracheal cannula. The drug-resistant rates of aztreonam. carbenicillin, timentin and cefoperazone were increasing too, but it was no significantly. Drug-resistant rates of pseudomonas aeruginosa for ceftazidime and impenem were not changes. Conclusion:Drug-resistant rats of pseudomonas aeruginosa were increasing in the elder patients with tracheal incision compared with tracheal cannula, but drug-resistant rates of pseudomonas aeruginosa for ceftazidime and impenem were not changes.

关 键 词：气管内插管法 气管切开术 细菌感染 铜绿假单胞菌 抗生素 耐药性 

分 类 号：R978.1[医药卫生—药品] R378.991[医药卫生—药学]