酸枣仁及壳药理作用与临床观察  

PHAMACOLOGICAL ACTION AND CLINICAL OBSERVATION OF ZIZYPHUS JUJUBA MILL VAR SPINOSUS HU.AND ITS SHELL

作　　者：李庆华 吴尚魁[1] 刘鹤香[1] 张星跃 刘春霞[1] 肖振民[1] 

机构地区：[1]新乡医学院基础医学部药理教研室 [2]新乡医学院一附院

出　　处：《新乡医学院学报》1991年第1期19-22,共4页Journal of Xinxiang Medical University

摘　　要：用酸枣仁及壳对小鼠进行了镇静实验,同时对生熟枣仁做了比较。结果表明:炒仁,生仁及壳均能抑制小鼠的自主活动,加强戍巴比妥钠、硫喷妥钠对中枢神经系统的抑制作用(P<0.05),并可对抗安钠咖对小鼠的兴奋作用(P<0.05),而壳的作用比仁弱,但随浓度增大作用增强。仁及壳均不能对抗戊四氮的惊厥作用(P>0.05),炒仁与生仁的镇静作用无明显差异。临床治疗失眠等症,生熟枣仁之间亦无明显差异。The sedative experiment of zizyphus jujuba and its shell vas was studied in mice。The results show that all the crude,the prepared and the shell can inhibit the automatic activi- ties of the mice significantly,and can strenghten the depressent effect of pentobarbital sodioum and thiopentone sodium to the central nervous systim(P<0.05)and antigonize the cental effection of caffein and sodium benzoate on mice(P<0.05).The action of shell is weaker than mill,but the action of shell is strenghthen along with it's concentrintion increased.They can not angtigonize the convulsion of cardiazol(P>0.05).The experi- ment show that the crude and the prepared dugs have not significant different.Clinical ob- servation show that the crude and the prepared have not significant difference.

关 键 词：酸枣仁 酸枣壳 镇静实验 疗效 

分 类 号：R282.710.5[医药卫生—中药学]