再狭窄与低强度激光治疗  

Restenosis and Low-Intensity Laser Therapy

作　　者：温静霞[1] 张杰[1] 等 

机构地区：[1]军事医学科学院放射医学研究所，中国北京100850

出　　处：《激光生物学报》2002年第3期236-240,共5页Acta Laser Biology Sinica

摘　　要：再狭窄是困扰冠心病介入治疗的主要问题 ,目前尚无完善的解决方法。低强度激光是可用于血管内照射的一种照射源 ,以其不发热 ,非损害的光生物学过程为特征 ,应用更为安全、有效和简便易行 ,而且低强度激光已在创伤修复等领域应用多年 ,证明可以促进伤口愈合或调节细胞生理过程。本文概述了再狭窄发生机制 ,探讨了低强度激光用于预防再狭窄的可能机理 ,总结了有关动物试验和初期临床应用的结果 ,认为低强度激光作为一种血管成形术后再狭窄的防治手段 ,无疑具有良好的前景。Percutaneous transluminal coronary angioplasty(PTCA) heralded a new era and launched the field of interventional cardiology.However,the over-compensatory wound healing response to angioplasty causing restenosis significantly limits the long-term success.The problem has not been well solved now.Recently,low-intensity laser causes much attention as a new way to prevent the restenosis.This review outlines the possible mechanisms,summarizes the results of animal studies and early clinic applications,concludes that low-intensity laser as a method to prevent restenosis has promising future.

关 键 词：治疗 低强度激光 再狭窄 血管成形术 PTCA 

分 类 号：R543.05[医药卫生—心血管疾病] R454.2[医药卫生—内科学]