体外不同频率高强度聚焦超声的生物学焦域  

Biological Focal Region in Vitro Induced by Different frequency of High Intensity Focused Ultrasound

作　　者：刘宝琴[1] 熊树华[1] 王智彪[1] 李发琪[1] 马平[1] 涂静秋[1] 龚小波[1] 伍烽[1] 白晋[1] 

机构地区：[1]重庆医科大学超声医学工程研究所,重庆市400016

出　　处：《中国超声医学杂志》2002年第6期417-420,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家自然科学基金资助 (资助号 :39770 841 )

摘　　要：目的 :探讨 HIFU体外不同频率的工作探头定位损伤牛肝组织的生物学焦域的定量关系。方法 :频率为 1.0 MHz及 1.6 MHz探头在相同输出功率时 ,定位损伤同一深度新鲜离体牛肝 ,测量并比较损伤灶的体积。结果 :随着辐照时间的延长 ,HIFU生物学焦域体积增加 ;1.0 MHz探头的 EEF大于 1.6 MHz探头的 EEF。结论 :在辐照深度相同时 ,1.6 MHz探头比 1.0 MHz探头的治疗效率更高。Objective:To explore biological focal region in calf liver quantitatively while exposed to ultrasound with frequency series Methods:In the same depth of calf liver was irradiated by ultrasound with a frequency of 1 0MHz and 1 6MHz respectively, at same output power Volume of necrosis was determined and compared Results:Volume of focal region were increased with elongation of duration , compared focal necrosis ascribed to 1 6MHz, those resulted from 1 0MHz were enlarged Conclusions:Efficacy of ablation with 1 6MHz was higher than that with 1 0MHz , while focuses where equal in depth

关 键 词：高强度聚焦超声 生物学焦域 能效因子 临床应用 

分 类 号：R445.1[医药卫生—影像医学与核医学]