长碳链脂肪酸-N-(四氢噻唑-2-硫酮)甲酯系列化合物的合成及表征  

Synthesis and characterization of long chain fatty acid-N-hydroxymethylthiazolidine-2-thione methylesters

作　　者：雷远江[1] 欧阳健明[1] 李毅群[1] 郑文杰[1] 唐渝[1] 

机构地区：[1]暨南大学化学系,广州510632

出　　处：《化学试剂》2002年第3期149-150,188,共3页Chemical Reagents

基　　金：国家自然科学基金重点项目(2 0 0 3 1 0 1 0 );教育部重点科学技术项目 (1 998-1 2 1 );广东省自然科学基金(980 898)

摘　　要：设计合成了 4种可作为 Langmiur-Blodgett膜 (简称 LB膜 )成膜材料的新的长碳链脂肪酸 -N-(四氢噻唑 -2 -硫酮 )甲酯类化合物 ,其中长碳链脂肪酸分别为十二烷酸、十四烷酸、十六烷酸和十八烷酸。利用噻唑杂环上氨基氢的活性进行羟甲基化制备得到相应的醇化物 ,再与酰氯反应得到相应的一系列长碳链杂环化合物。通过元素分析、IR、1 HNMR。Four new long chain fatty acid of N hydroxymethylthiazolidine 2 thione methylesters type were designed and synthesized These esters can be used as material for Langmiur Blodegtt (LB) film preparation The long chain fatty acids include dodecanoic acid,tetradecanoic acid,hexadecanoic acid,and octadecanoic acid.The hydroxymethylation with active aminohydrogen in thiazole heterocyclic ring was used to prepare alcoholates Alcoholysis of the alcoholates with the use of acid chloride gave the long chain heterocyclic compounds The structure of the four unreported compounds was characterized by elementary analysis along with IR and 1H NMR spectral data

关 键 词：长碳链脂肪酸-N-(四氢噻唑-2-硫桐)甲酯 合成 表征 四氢噻唑-2-硫酮衍生物 羟甲基化 醇解 LB膜 成膜材料 

分 类 号：O626.25[理学—有机化学]