合成4-硝基-4′-氯二苯甲酮的新途径  

A new route for the synthesis of 4-nitro-4′-chlorobenzophone

作　　者：黄向红[1] 

机构地区：[1]温州大学化学与环境工程学院,温州325027

出　　处：《化学试剂》2002年第3期171-172,共2页Chemical Reagents

摘　　要：对硝基苯甲酸和二氯亚砜在氯苯中回流数小时氯化后 ,在无水三氯化铝作用下酰化 ,得到 4-硝基 -4′-氯二苯甲酮。通过条件试验和正交试验进行优化。产品结构经 IR、1 HNMR。In chlorobenzene,4 nitrobenzoic acid and sulfuryl chloride was refluxed at 131℃ for 7 h.Then acylation was carried out in the presence of anhydrous alchlor at 80℃ for 2 h that gave 4 nitro 4′ chlorobenzophone in 65.18% yield.The reaction conditions were optimized by orthogonal experiments.The structure of the product was confirmed with IR, 1HNMR and MS.

关 键 词：合成 4-硝基-4′-氯二苯甲酮 酰氯化 酰化 工艺条件 对硝基苯甲醛 二氯亚砜 

分 类 号：O625.614[理学—有机化学] O625.612[理学—化学]