双(1,4-二酰基氨基硫脲)化合物的合成  

Synthesis of series of bis(1,4-diacylthiosemicarbazide)

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作  者:杨海君[1] 颜江[1] 宜云遐[1] 吴江[1] 

机构地区:[1]四川大学化学学院,四川成都610064

出  处:《化学研究与应用》2002年第3期325-325,共1页Chemical Research and Application

摘  要:A series of bis(1,4 diacylthiosemicarbazide) compounds were synthesized in good yields by the condensation of dicarbonyl isothiocyanate 2 with benzoic hydrazide or dicarbonyl dihydrazide 5 with benzoic isothiocyanate 2′.And the intermediates 2,5 can be easily prepared from the original dicarboxyl acids.With two thiosemicarbazide side chains,these bis (1,4 diacylthiosemicarbazide) compounds may possess good biological activity.A series of bis(1,4 diacylthiosemicarbazide) compounds were synthesized in good yields by the condensation of dicarbonyl isothiocyanate 2 with benzoic hydrazide or dicarbonyl dihydrazide 5 with benzoic isothiocyanate 2′.And the intermediates 2,5 can be easily prepared from the original dicarboxyl acids.With two thiosemicarbazide side chains,these bis (1,4 diacylthiosemicarbazide) compounds may possess good biological activity.

关 键 词:双(1 4-二酰基氨基硫脲)化合物 合成 二酰氯 异硫腈酸二酰酯 二酰肼 

分 类 号:O623.664[理学—有机化学]

 

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