职业性氟接触工人口服海尔福前后血清生化变化的研究  

Serum biological changes in workers exposed to fluorine before and after being given Haierfu Oral Liquid

作　　者：韦耀东[1] 张树球[1] 农嵩[1] 李朝敢[1] 黄受宪 唐任光[1] 梁淑英[1] 蒙金秋[1] 朱晓莹[1] 

机构地区：[1]右江民族医学院,广西百色533000 [2]广西平果县氟化盐厂,广西平果531400

出　　处：《右江民族医学院学报》2002年第3期336-337,共2页Journal of Youjiang Medical University for Nationalities

摘　　要：目的　观察高氟环境作业工人服用海尔福口服液前后血清生化指标的变化 ,以验证其防治效果。方法　口服海尔福 1 5天 ,每天 3次 ,测定服药前后血清丙氨酸氨基转移酶 (ALT)活性和丙二醛 (MDA)、血清氟离子 (F- )及钙、磷等含量。结果　服药后血清ALT活力、MDA含量明显下降 (P <0 .0 0 1 ) ;血F- 下降不明显 (P >0 .0 5) ;钙含量下降 ,磷含量升高 (P <0 .0 0 1 ) ,但仍在正常范围内。Objective To confirm the preventive efficacy of Haierfu Oral Liquid on workers exposed to fluorine by observing serum biological changes before and after taking Haierfu Oral Liquid. Methods The workers were given Haierfu Oral Liquid for 15 days, three times a day. Then the serum alanine transaminase (ALT) activity, and the content of malondialdehyde (MDA), serum fluorine ion (F -), calciun (Ca 2+ ), and phosphorus (P) before and after taking Haierfu Oral Liquid were detected. Results After taking Haierfu Oral Liquid, the serum ALT activity and MDA content decreased significantly (P<0.001); serum F - decreased slightly (P>0.05); the content of Ca 2+ lowered and P elevated (P<0.001) within normal range. Conclusions Haierfu Oral Liquid could protect workers exposed to fluorine from liver injury and resist oxidation.

关 键 词：海尔福口服液 氟 丙氨酸转氨酶 丙二醛 

分 类 号：R135[医药卫生—劳动卫生]