酒精性脂肪肝患者血清酶检测的临床意义  

Determination of Serum Enzyme in Alcoholic Fatty Liver and Clinical Implication

作　　者：程薇莉[1] 丁茗敏[1] 何嫱[1] 张桂兰[1] 赵瑛[1] 

机构地区：[1]济南军区青岛第一疗养院,266071

出　　处：《中国康复》2002年第2期101-102,共2页Chinese Journal of Rehabilitation

摘　　要：目的 :检测酒精性脂肪肝 (AFL)患者血清γ 谷氨酰转肽酶 (GGT)、丙氨酸转氨酶 (ALT)、天门冬氨酸转氨酶 (AST)、碱性磷酸酶 (ALP)及AST/ALT的含量 ,以探讨其变化与酒精性脂肪肝损伤程度的关系和早期诊断的价值。方法 :AFL患者 2 32例 ,采用Bayer公司生产的RA 10 0 0型全自动生化分析仪和国产试剂盒进行测定。结果 :2 32例患者的血清GGT、ALT、AST含量明显高于对照组 (均P <0 .0 0 1) ,其中以GGT增高最为明显 ,发病年龄有年青化的趋势。结论 :血清GGT检测是诊断AFL较为敏感且具有一定特异性的指标。提醒人们必须重视过量饮酒对身体健康所造成的危害。Objective: To study the correlation between the changes in the contents of serum GGT, ALT, AST, ALP, AST/ALP in alcoholic fatty liver and the liver damage. Methods: By using Beyer RA 1000 Automatic biochemical analyzer, the contents of serum GGT, ALT, AST, ALP, AST/ALP in the patients with alcoholic fatty liver were determined. Results: The contents of serum GGT, ALT, AST, especially GGT content, were significantly higher in the patients with alcoholic fatty liver than in the control group (all P < 0.001 ). Conclusion: Serum GGT is a sensitive and specific indicator for the diagnosis of alcoholic fatty liver.

关 键 词：酒精性脂肪肝 血清酶 Γ-谷氨酰转肽酶 AFL GGT 诊断 临床分析 

分 类 号：R446.1[医药卫生—诊断学]