COPD缓解期并慢性Ⅱ型呼吸衰竭长期家庭氧疗临床观察  

Clinical observation of long term oxygen therapy for COPD patients with chronic type Ⅱ respiratory failure in stable stage

作　　者：陈浩波[1] 

机构地区：[1]广东肇庆市第一人民医院呼吸内科,526021

出　　处：《中国基层医药》2002年第6期495-496,共2页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的　了解长期家庭氧疗 (LTOT)对缓解期合并慢性Ⅱ型呼吸衰竭的慢性阻塞性肺疾病(COPD)病人预后及生活质量的影响。方法　对 52例缓解期并慢性Ⅱ型呼吸衰竭的COPD病人根据其经济状况分为长期家庭氧疗组和非氧疗组 ,氧疗组每日吸氧时间≥ 1 5h ,非氧疗组未行氧疗。对两组病人进行连续 3年随访 ,每半年复查血常规、血气分析、肺功能。结果　氧疗组半年、1年后PaO2 及SaO2 显著高于非氧疗组 ,血红蛋白、红细胞压积显著低于非氧疗组 ;氧疗组每年平均住院次数显著低于非氧疗组 ;氧疗组 3年的病死率显著低于非氧疗组。结论　长期家庭氧疗对COPD缓解期并慢性Ⅱ型呼吸衰竭的病人能显著降低远期的病死率 。Objective To explore the effects of LTOT on prognosis and quality of life for COPD patients with chronic type Ⅱ respiratory failure in stable stage.Methods 52 COPD patients with chronic type Ⅱ respiratory failure in stable stage were divided into LTOT group and non LTOT group according to their economic condition.LTOT group accepted oxygen therapy more than 15 hours per day.Non LTOT group did not accept oxygen therapy.The two groups were followed up for 3 years with accepted examination of blood routine,blood gas analysis and lung function per 6 months.Results PaO 2 and SaO 2 of LTOT group were higher than that of non LTOT group significantly,Hb and HCT of LTOT group were lower than that of non LTOT group significantly after 6 months and 1 year.Average time in hospital of LTOT group was lower than that of non LTOT group significantly,and 3 years mortality rate of LTOT group was lower than that of non LTOT group significantly.Conclusion LTOT can elevate quality of life and decline mortality rates of COPD patients with chronic type Ⅱ respiratory failure.

关 键 词：COPD 缓解期 慢性Ⅱ型呼吸衰竭 家庭氧疗 预后 生活质量 

分 类 号：R563.8[医药卫生—呼吸系统] R459.6[医药卫生—内科学]