三氯生合成的研究(Ⅰ)  

Study on the Synthesis of Triclosan(Ⅰ)

作　　者：冯荣秀[1] 宋健[1] 李效军[1] 陈磊[1] 王军波[1] 石巍[1] 王琨[1] 

机构地区：[1]天津大学药物科学与技术学院,天津300072

出　　处：《化学工业与工程》2002年第3期229-232,共4页Chemical Industry and Engineering

摘　　要：三氯生是一种优异的杀菌添加剂 ,广泛用于卫生保健等领域。其合成一般是以2 ,4 -二氯苯酚和 2 ,5-二氯硝基苯为原料 ,经过醚化、硝基还原、重氮化及水解等几步反应。本文研究了醚化。Triclosan is a kind of bactericides that has found applications in hygiene and health. Synthesis of triclosan from 2,4-Dichlorophenol and 2,5-Dichloro-nitrobenzene usually involves etherization, reduction of nitro group, diazotization and hydrolysis. The first two steps were studied in this paper.

关 键 词：三氯生 2 4-二氯苯酚 2 5-二氯硝基苯 醚化 硝基还原 

分 类 号：O623.425[理学—有机化学]