头低位卧床及饮用含电解银离子水对肠道双歧杆菌的影响  

Effects of Head Down Bed Rest or Drinking Water Containing Electrolytic Silver ion on Intestinal Bifidobacteria

作　　者：李志霞[1] 刘成林[1] 于晓影 谢力勤[1] 

机构地区：[1]航天医学工程研究所,北京100094 [2]哈尔滨卫生防疫站食品二科,黑龙江哈尔滨150010

出　　处：《航天医学与医学工程》2002年第3期186-188,共3页Space Medicine & Medical Engineering

摘　　要：目的观察头低位卧床以及电解银离子 (航天饮用水消毒剂之一 )对肠道双歧杆菌的影响。方法1) 5名健康男性青年进行 2 1d的头低位 - 6°卧床实验 ,收集卧床前后的粪便 ,测双歧杆菌数量。 2 ) 4组小鼠分别饮用不含银纯净水、银含量为 0 .2 0、0 .40、0 .60mg/L的饮水 1月 ,测肠粪中双歧杆菌的数量。3 ) 7名健康男性志愿者 ,连续饮用含银量 0 .2 0mg/L的饮水 16d ,取实验前、饮水第 3、10、16天的粪便 ,测双歧杆菌数量。结果 1 )卧床后被试者粪中双歧杆菌的数量 (lgn/g)较卧床前呈显著性减少 (P <0 .0 1)。 2 )小鼠肠粪混合样中的双歧杆菌数 (lgn/g)与饮水中的银离子含量呈显著性负相关 (r =- 0 .992 ,P <0 .0 1)。 3 )被试者饮用含银离子水后粪中双歧杆菌的含量较饮用前呈显著性减少 (P <0 .0 5 )。Objective To investigate the effect of head down bed rest(HDBR) or electrolytic silver ion on intestinal bifidobacteria in men and mice. Method Three tests were conducted.Counts of bifidobacteria in feces were made in:1) 5 male healthy volunteers after 21 d -6° HDBR.2) 4 groups of mice drank water containing no Ag +,0 20,0.40 and 0.60 mg/L of Ag + respectively for 1 month. 3) Seven male healthy volunteers drank water containing 0.20 mg/L of silver ion for 16 days. Result 1) The count of bifidobacteria after HDBR[8.08±0.82(lgn/g)] was significantly decreased as compared with the control group[8.72±0.82(lgn/g)](P<0.01). It suggests that HDT-6° bed rest might reduce the number of bifidobacteria in the human colon.2)The count of bifidobacteria in feces was negatively correlated with the silver ion concentration in the water (r=-0.992,P<0.01). 3) The count of bifidobacteria in feces after test [7.83±0.71(lgn/g)] was significantly decreased as compared with that before the test (8.91±0.84)(P<0.05). Conclusion It demonstrates that HDT-6° bed rest and electrolytic silver ion all might reduce the count of bifidobacteria in feces.

关 键 词：头低位倾斜 卧床实验 电解银离子 双歧杆菌 模拟失重 

分 类 号：R852.22[医药卫生—航空、航天与航海医学]