多波长系数法的研究与应用  被引量:17

STUDY ON THE MULTIWAVELENGTH COEFFICIENT SPECTROPHOTOMETRY AND ITS APPLICATION

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作  者:黄生红 

机构地区:[1]上海市金山县药品检验所,上海201500

出  处:《药学学报》1991年第5期395-398,共4页Acta Pharmaceutica Sinica

摘  要:在多组分光度分析的方法中,最小二乘法、Kalman滤波、因子分析等虽已能成功的消除组分间的相互干扰,不经分离直接定量,但均需有微机配套进行矩阵运算。而双波长、三波长法,虽然简单,但对于吸收光谱重叠严重的混合组分,则难以选出满足要求的波长;This paper reveals a general principle of multiwavelength spectrophotometry and puts forward a multiwavelength coefficient method to determine mixed components system. The determination of the coefficients and the connection between the coefficients with the method are discussed in the paper. Using several groups of coefficients,according to the method, a mixed components of chlorpromazine hydrochloride and promazine hydrochloride were assayed at the same time. The laboratory results of recoveries indicates that the precision and the accuracy are good, and, different coefficients do not make a notable impact on the method.

关 键 词:多波长 系数法 药物检验 

分 类 号:R927.1[医药卫生—药学]

 

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