差示—线性组合导数光谱法测定扑咳灵片中扑尔敏和溴化丙胺太林  

DETERMINATION OF CHLORPHENAMINE AND PROPANTHELINE BROMIDE IN PUKELING TABLETS B(?) DIFFERENTIAL-LINEAR COMBINATION DERIVATIVE SPECTROPHOTOMETRY

作　　者：林黎明 张乃吉 王焕玉 

机构地区：[1]潍坊市药品检验所,潍坊261041 [2]山东省药品检验所,济南250012

出　　处：《药学学报》1991年第6期451-457,共7页Acta Pharmaceutica Sinica

摘　　要：本文提出了差示一线性组合导数光谱法用于测定混合组分体系的基本原理和实验方法。并试用本法消除了扑尔敏、溴化丙胺太林、灵芝粉及附加剂之间的相互干扰,从而分别测定了扑咳灵片巾扑尔敏和溴化丙胺太林的含量,其平均回收率分别为100.2±1.49％(CV)和99.89±1.03％(CV)。其精密度、准确度均好。This paper provides the basic principle and experimental technique of differential-linear combination equal value derivative spectrophotometry. Quantitative analysis of three or four component - mixture can be done without separation. This method was investigated to assay the contents of chlorphenamine and propantheline bromide in Pukeling tablets by using UV-210A spectrophotometer. The average recoveries of chlorphenamine and propantheline bromide were 100. 2±1.49% (CV) and 99.89± 1.03% (CV)respectively. The results showed that it not only can effectively remove distrubances from each other, but also give higher sensitivity and accuracy.

关 键 词：光谱法 扑咳灵片 扑尔敏 含量 

分 类 号：R927.2[医药卫生—药学]