茜草醇提物的解热镇痛作用  

Studies on the Analgesic and Antipyretic Acyion of Ethanol Extract of Rubia Cordifolia L.

作　　者：刘成立[1] 许兰芝[2] 陈维宁[2] 高尔[2] 张薇[2] 

机构地区：[1]潍坊医学院附属潍坊市人民医院,山东潍坊261042 [2]潍坊医学院药理学教研室

出　　处：《潍坊医学院学报》2002年第1期4-5,共2页Acta Academiae Medicinae Weifang

基　　金：潍坊市科委资助课题 (课题号 :2 0 0 0 0 82 )

摘　　要：目的　观察茜草醇提物的解热镇痛作用。方法　用热板法、电刺激法、扭体法测定茜草醇提取物 (相当于生药 1.5g kg灌胃 )对小鼠痛阈值的影响及茜草醇提物对伤寒菌苗所致发热家兔的解热作用。结果　多种实验方法均显示茜草醇提取物明显提高小鼠的痛阈值 ,并降低伤寒菌苗所致发热家兔的体温。结论　茜草醇提取物有较强的解热镇痛作用。Objective The analgesic and antipyretic action of ethanol extract of Rubia cordifolia L.(EER).Method Using hot plate (55℃) and 0.7% acetic acid 10ml·kg -1 and electrical stimulation algogenic method in mice,typharatyphoid vaccine induced fever in rabbits,the analgesic and antipyretic action of EER was studied.Result The analgesic action of EER in mice was showed by over multiple method,the antipyretic action of EER in rabbits were showed.Conclusion EER has obvious analgesic and antipyretic action.

关 键 词：茜草乙醇提取物 解热作用 镇痛作用 

分 类 号：R285.5[医药卫生—中药学]