白细胞介素1α测定对结核性、恶性胸腔积液的鉴别意义  

Clinical significance of detecting interleukin-1 alpha of pleural effusion in differentiating tuberculous and malignant pleural effusions

作　　者：赵云峰[1] 王英年[1] 高岱清[1] 张春玲[1] 马学真[1] 刘加洪[1] 

机构地区：[1]青岛大学医学院第二附院结核肺病研究所,山东青岛266042

出　　处：《中国实验诊断学》2002年第3期168-169,共2页Chinese Journal of Laboratory Diagnosis

摘　　要：目的　测定结核性及恶性胸腔积液患者胸液白细胞介素 1α水平 ,探讨其对鉴别良恶性疾病的意义。方法　采用酶联免疫吸附试验法 (ELISA法 )测定 14例结核性胸液患者及 30例恶性胸液患者胸液的白细胞介素 1α含量。结果　恶性胸液患者胸液白细胞介素 1α含量 (6 6 6± 18 4ng/L)明显高于结核性胸液患者胸液白细胞介素 1α(38 3±17 9)ng/L ,P <0 0 5。结论　测定胸液白细胞介素 1α水平对鉴别结核性、恶性胸液有较大的帮助。Objective To explore the clinical significance of detecting interleukin?lalpha of pleural effusion in differentiating tuberculous and malignant diseases. Methods Interleukin?1 alpha of pleural effusion in 14 patients with tuberculous pleurisy and 30 patients with malignant pleural effusion was detected by ELISA method.Results Interleukin?1 alpha of pleural effusion in patients with malignant pleural effusion(66 6±18 4 ng/L) was much higher than that of pleural effusion(38 3±17 9 ng/L) in tuberculous pleurisy. Conclusion Detecting interleukin?1 alpha of pleural effusion might be helpful for differentiating tuberculous and malignant diseases.

关 键 词：胸腔积液 白细胞介素1Α 酶联免疫吸附试验 

分 类 号：R446.6[医药卫生—诊断学]