人工肝支持系统治疗重型病毒性肝炎的研究  

Treatment of severe viral hepatitis with artificial liver support system

作　　者：李保森[1] 辛绍杰[1] 邢汉前[1] 赵军[1] 邹正升[1] 张彬[1] 陈德永[1] 毛远丽[1] 

机构地区：[1]解放军第三○二医院感染三科,北京100039

出　　处：《中华实验和临床病毒学杂志》2002年第2期157-159,共3页Chinese Journal of Experimental and Clinical Virology

摘　　要：目的　研究人工肝支持系统治疗重型病毒性肝炎的方法及疗效。方法　利用Baxter 550人工肾和Biologic DTsystem进行人工肝支持系统 (ALSS)治疗肝炎患者 83例 ,其中重型肝炎患者66例。结果　治疗后平均胆红素、ALT、AST、BUN、Cr及内毒素较治疗前均有明显下降。 66例重型肝炎患者中治愈好转 31例 (47 0 % ) ,死亡或自动出院 35例 (53 0 % ) ,对照组 1 81例重型肝炎患者中治愈好转 50例 (2 7 6 % ) ,死亡或自动出院 1 31例 (72 4% )。Objective To investigate the method and therapeutic efficacy of artificial liver support system (ALSS) in treatment of severe viral hepatitis.Methods A total of 83 patients including 66 with severe viral hepatitis were treated with ALSS using Baxter\|550 artificial kidney and Biologic\|DT system.Results The levels of mean bilirubin,ALT,AST,BUN,Cr and endotoxin was significantly decreased after the treatment.Of the 66 patients with severe viral hepatitis,31(47.0%) had improvement in symptoms and 35 (53.0%) died or left hospital.In the control group,50(27.6%) out of the 181 had improvement in symptoms and 131(72.4%) died or left hospital.Conclusion ALSS could exert certain therapeutic effects on severe viral hepatitis.

关 键 词：人工肝支持系统 治疗 重型病毒性肝炎 研究 

分 类 号：R512.6[医药卫生—内科学]