脉冲多普勒超声心动图对高血压病人冠脉血流储备的测定  

Coronary Flow Reserve in Patients with Essential Hypertension Determined by PDE

作　　者：姜克新[1] 徐长新[1] 赵丽君 

机构地区：[1]中国医科大学附属第二医院超声科,辽宁沈阳110004 [2]辽宁省兴城市妇幼保健院

出　　处：《中国医学影像技术》2002年第6期577-579,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的　应用经胸脉冲多普勒超声心动图 (PDE)测定高血压病人的冠脉血流储备功能 (CFR)。方法　 2 0例正常人和 3 5例无并发症的轻中度原发性高血压病人经静脉注射潘生丁 ,测量用药前后左冠状动脉主干舒张期峰值速度 ,计算其比值作为冠脉血流储备指标。结果　高血压病人无论是否伴有心肌肥厚均伴有冠脉血流储备指标D/RPDV的减低 ,差异显著 (P <0 .0 1)。Purpose To determine coronary flow reserve (CFR) in patients with essential hypertension by transthoracic pulsed Doppler echocardiography (PDE). Methods Dipyridamole was infused in peripheral vein of 20 normal subjects and 35 patients with mild to moderate essential hypertension without complications. Peak diastolic flow velocity (PDV) was obtained at rest (R) and after dipyridamole (D) infusion. The ratio of diastolic flow velocity (D/R) was calculated as an index of CFR in left coronary artery. Results D/R PDV was significantly lower in the patients with hypertension accompanied with hypertrophy or non hypertrophy than that of the normal ( P <0.01).Conclusion Essential hypertension is often accompanied by impairment in coronary flow reserve.

关 键 词：高血压 左室肥厚 左室重量指数 脉冲多普勒超声心动图 冠脉血流储备 

分 类 号：R544.1[医药卫生—心血管疾病] R445.1[医药卫生—内科学]