心脉通对急性心肌梗死患者冬眠心肌的保护作用  

Discussion of Xinmaitong capsule on protective function and mechanism of AMI patients' hibernating myocardium

作　　者：孟君[1] 冯君[1] 丘瑞香[1] 蓝军[2] 贺敬波[3] 

机构地区：[1]中山医科大学附属第一医院中医科,广东省广州市510080 [2]广东省东莞市石龙人民医院心内科,523321 [3]广东省深圳市宝安区人民医院中医科,518000

出　　处：《现代中西医结合杂志》2002年第12期1091-1093,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的 :探讨心脉通胶囊对急性心肌梗死 ( AMI)患者冬眠心肌的保护作用及作用机理。方法 :将 46例 AMI患者随机分为心脉通组 ( 2 3例 ,常规西药加心脉通胶囊治疗 )与对照组 ( 2 3例 ,单用常规西药治疗 ) ,观察治疗前后 AMI患者心脏收缩功能、室壁运动异常指数、QT离散度的变化。结果 :心脉通组左室运动功能改善及 QT离散度下降程度与对照组相比有显著性差异 ( P<0 .0 5 )。结论 :心脉通胶囊不但可促进 AMI患者梗死区冬眠心肌的电苏醒 ,而且还可促进冬眠心肌的电苏醒 。Objective: It is to explore the protective function and mechanism of Xinmaitong capsule on the hibernating myocardium of AMI patients. Methods: Forty-six patients with AMI were randomly divided into two groups. Twenty-three patients were in Xinmaitong group and treated with regular west medicine and Xinmaitong capsule. The other twenty-three patients were in control group and only treated with regular west medicine. The changes of heart systolic function, ventricular wall dyskinasia index and QT dispersion of AMI patients were observed. Results: The changes of left ventricular dyskinasia improving and QT dispersion decreasing in Xinmaitong group had significant different compared with those in control group (P<0.05). Conclusion: Xinmaitong capsule can improve electricity revival and force revival of the hibernating myocardium in infarction areas of AMI patients and has significant effect on regained function of the hibernating myocardium.

关 键 词：保护作用 心脉通胶囊 急性心肌梗死 冬眠心肌 

分 类 号：R542.22[医药卫生—心血管疾病]