声学密度定量技术与冠状动脉造影术的对比研究  

A Comparative Study on Acoustic Densitometry (AD) Technique and Coronary Artery Angiography

作　　者：袁文利[1] 黄灿亮[1] 万征[1] 周贵明[1] 林青[1] 李晓春[1] 张文娟[1] 蔡衡[1] 张殿芬[1] 赵俊雪[1] 

机构地区：[1]天津医科大学总医院心内科,300052

出　　处：《天津医药》2002年第6期326-327,共2页Tianjin Medical Journal

摘　　要：目的:探讨声学密度定量（AD）技术评价正常、狭窄及闭塞血管支配区域心肌的组织特征。方法:对疑诊冠心病的64例患者,根据冠状动脉造影结果将192支冠状动脉分组:正常组（A组）、狭窄组（B组）、闭塞组（C组）,检测其相应血管支配区域心肌的背向散射积分参数。结果:与A组相比,B组心肌的背向散射积分的标化值（IBS％）增高;而背向散射积分周期变化幅度（CVIB）减小;C组心肌的IBS％增高更明显;CVIB减小也更明显;且14支闭塞血管支配区域心肌的CVIB曲线与正常节段呈反向,N-delay在B组及C组明显延长。同一参数组间比较差异均有显著性（P<0.01）。结论:AD技术能客观反映正常、狭窄及闭塞冠状动脉供血区域心肌的不同组织特性变化,对鉴别冠心病不同病变心肌的灌流特征具有一定的诊断意义。Objective: To evaluate the value of acoustic densitometry (AD) technique in detecting the changes of tissue characterization of myocardibyum which supplied normal, stenosis, and occluded artery. Methods: One hundred and ninety-two coronary arteries from 64 patients were divided into normal (group A), stenosis (group B), and occluded groups (group C). Myocardia of three groups were measured with AD parameters. Results: IBS% increased and CVIB decreased in myocardium in group B compared with that in group A(P<0.01), and were significantly higher than that in group C(P<0.01). CVIB curve of 14 segments supplied by occluded coronary artery appeared reverse change. N-delay prolonged significantly in groups B and C (P<0.01). Conclusion: AD technology can detect the change of tissue characterization in myocardium supplied by normal, stenosis, and excluded artery. The index is useful in identification of myocardial disease with coronary artery disease.

关 键 词：声学密度定量技术 冠状动脉造影术 对比研究 冠状动脉疾病 冠心病 诊断 

分 类 号：R541.4[医药卫生—心血管疾病]