中老年人群脊椎骨折患病危险因素研究  

Comparison Study on Risk Factors of Vertebral Fracture between Men and Women in Middle-aged and Elderly Population in Parts Area of China

作　　者：李宁华[1] 区品中[2] 朱汉民[3] 杨定焯[4] 赵晰[5] 张大新[6] 李恩[7] 马翰章[2] 邓力平[2] 张韵[3] 朱晓颖[3] 安珍[4] 刘力克[4] 郑蘋如[5] 李颖新[5] 

机构地区：[1]卫生部北京医院流行病学研究室,北京100730 [2]广州医学院第二附属医院骨科 [3]上海华东医院 [4]四川华西医科大学附四院骨质疏松科 [5]长春白求恩医科大学附一院干部病房 [6]卫生部中日友好医院物理康复科 [7]河北医科大学生物化学教研室

出　　处：《中国公共卫生》2002年第7期782-784,共3页Chinese Journal of Public Health

基　　金：国家"九五"科技攻关计划资助项目 (96 90 6 0 5 0 1 )

摘　　要：目的　了解中国中老年人群脊椎骨折患病危险因素 ,为脊椎骨折的预防和治疗提供依据。方法　采用分层多阶段整群抽样方法对中国五大行政区 5 10 3例 5 0岁以上男女人群进行胸腰椎侧位平片 ,骨密度测量和问卷调查 ,对14 0余个变量进行多因素非条件Logistic回归分析 ,得出各危险因素的比数比值 (OddsRatio ,OR)。结果　筛选出 19个影响我国部分地区脊椎骨折患病因素 ,其中 ,年龄因素 (OR =1 0 3～ 1 0 7)为男女共同危险因素 ;服用钙剂 (OR =0 6 2～ 0 80 )和骨密度高 (OR =0 0 0～ 0 15 )为男女共同的保护性因素。脑血管病 ,喜吃咸食物等危险因素和住房朝阳 ,常吃面类 ,常吃鱼类 ,走路速度快等保护性因素在男性中出现 ;长期卧床危险因素和年轻时高 (cm) ,服维生素D ,服女性激素 ,右手握力大 (公斤 )保护性因素在女性中出现。结论　我国中老年人男女脊椎骨折患病危险因素中有共同的暴露因素 ,同时 。Objective To understand the risk factors of vertebral fracture in the middle aged and the elderly in China to provide bases data for the prevention and treatment of vertebral fracture.Methods Lateral spine films,bone mineral destiny was measured and questionnaire was surveyed from 5 103 people aged above 50 years old in five administrative areas in China, by the stratified multi steps cluster sampling method.About 140 variables were analyzed by the non conditional logistic regression to obtain OR of all kints of risk factors.Results The common risk factors for men and women were age ( OR =1\^03～1\^07).The common protective factors for men and women were intake of calcium( OR =0\^62～0\^80)and high bone mineral density( OR =0\^00～0\^15);Some statistically significant correlation existed in men,for example,risk factors of brain vascular diseases,high intake of salted food and protective factors of residence for sunshine,high intake of wheat powder,high intake of fish and quickly walk;another statistically significant correlation existed in women,for example,risk factors of lying in bed for long time and protective factors of height when young,intake of vitamin D and women hormones and right superiority wrist.Conclusion Some common risk factors for vertebral fracture did exist in men and women,but these were some varieties of riak factors in men and women.Thus,the important reference data were provided to the strategy of prevention and treatment on vertebral fracture.

关 键 词：中老年人群 脊椎骨折 危险因素 

分 类 号：R683.2[医药卫生—骨科学]