水杨酸苯酯的合成新方法研究  

Catalytic Synthesis of Phenyl Salicylate by DMAP-DCC

作　　者：丁盈红[1] 张红[1] 伍焜贤[1] 佘志刚[1] 李思[1] 

机构地区：[1]广东药学院,广州510224

出　　处：《山西化工》2002年第2期10-11,共2页Shanxi Chemical Industry

摘　　要：4-二甲氨基吡啶 (DMAP)作催化剂 ,二环己基碳二亚胺 (DCC)作脱水剂 ,常温下用水杨酸和苯酚直接合成了水杨酸苯酯。实验结果表明 ,此反应条件温和 ,反应时间短 ,后处理容易 。dimethylpyridine (DMAP) was used as catalyst for the synthesis of phenyl salicylate from salicylic acid and phenol.Dicyclohexylcarbodiimide (DCC) was also used as dehydrating agent.The results showed that the appropriate conditions are reaction temperature 20 ℃,molar ratio of phenol to salicylic acid to DCC 1∶1∶1,reaction time 3.0 h,the weight ration of DMAP to phenol 3 %.yield was about 81.3 %.

关 键 词：水杨酸苯酯 合成 水杨酸 苯酚 酯化 4-二甲氨基吡啶 二环己基碳二亚胺 催化剂 

分 类 号：O625.523[理学—有机化学]